Positive (1-3) B-d-Glucan and cross reactivity of fungal assays in coccidioidomycosis
نویسندگان
چکیده
منابع مشابه
Positive (1-3) B-d-glucan and cross reactivity of fungal assays in coccidioidomycosis.
Fungal antigen testing in immunosuppressed patients has emerged as a powerful diagnostic tool. Some assays are relatively nonspecific, and misinterpretation can have severe clinical consequences. Additionally, when new assays become commercially available it is important to evaluate the potential for cross reactivity. We recently observed several immunosuppressed patients with positive (1→3)-β-...
متن کاملSerum (1->3)-β-D-glucan measurement in coccidioidomycosis.
The serum (1→3)-β-d-glucan assay has emerged as an important diagnostic test for invasive fungal disease. The utility of this assay in coccidioidomycosis has not been previously studied. Using a cutoff value of ≥80 pg/ml, we found the sensitivity (43.9%), specificity (91.1%), positive predictive value (81.8%), and negative predictive value (64.1%) to be similar to those of the assay in diagnosi...
متن کامل(1-3)-β-D-Glucan vs Galactomannan Antigen in Diagnosing Invasive Fungal Infections (IFIs)
Invasive fungal infections (IFIs) are serious and often life-threatening complications in patients with haematological malignancies. Early diagnosis and the initiation of efficacious antifungal treatments could affect the prognosis of these patients. The detection of (1-3)-β-D-Glucan (BDG) could be a promising non-culture-based, noninvasive tool for IFI analyses in haemato-oncological patients,...
متن کاملAssessment of Β-d-(1→3)-glucan Assay for Diagnosis of Invasive Fungal Infec- Tions
Aim: Invasive fungal infections (IFIs) are associated with high mortality and morbidity. However, the diagnosis of IFIs in an immunocompromised host is difficult and often missed or delayed. Our aim was to investigate the feasibility of the (1→3)-β-DGlucan assay as a diagnostic complement for IFIs. Methods: We reviewed the records of all inpatients in various units at Erciyes University’s Medic...
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ژورنال
عنوان ژورنال: Medical Mycology
سال: 2014
ISSN: 1369-3786,1460-2709
DOI: 10.1093/mmy/myu077